Skip to main navigation Skip to main content
The University of Southampton
Public Policy|Southampton

Antidepressants for pain management in adults with chronic pain: a network meta-analysis

Overview

This project comprised of a systematic review and a network meta analysis of published randomised controlled trials testing antidepressants prescribed to people with Cochrane pain to reduce and manage their pain. The project found moderate evidence that duloxetine was effective in reducing pain in the short term, but there was insufficient evidence on long term effects and on side effects. All studies were evaluated for their methodological rigour. There was insufficient evidence to draw conclusions on any other antidepressant.

Anticipated policy impacts

The findings should influence the NICE guidelines for Primary Pain, Fibromyalgia, Back Pain, Neuropathic Pain and Osteoarthritis.

Outputs

A published paper .

Project Members

Project Lead: Tamar Pincus

Hollie Birkinshaw (Southampton), Friedrich CM, Cole P, Eccleston C, Serfaty M, Stewart G, White S, Moore RA, Phillippo D.

Are you involved in a research project? Click here

Find out more

Policy Briefs

Policy Briefs

Click to read UoS Students and Academics reflecting on their experience of engaging with PPS and policymakers.

Podcasts

Policy Podcasts

Click here to listen to our Policy Podcast series. In each episode we speak to the UoS researchers and experts, about their experiences in the domestic and foreign policies.

Engage

Ways to engage

Guidance on the many channels available to researchers to engage with policymakers.

Impact toolkit

Impact toolkit

Guidance on things to consider in the science to policy process and useful tips in planning and costing your impact activities.

Privacy Settings
Powered by Fruition